
The diet has a crucial role in modulating intestinal inflammation and the risk of inflammatory bowel disease, so the avoidance and/or reduction of proinflammatory foods is considered a good practice for disease prevention.
The CDED is a diet which exclude or limit exposure to foods that may negatively affect the microbiome or alter intestinal barrier function. The CDED is divided into three phases and they all include Partial Enteral Nutrition (PEN) from formula and mandatory foods to ensure high quality nutrition and changes in the bacteria of the gut: high quality lean protein, resistant starch and fibre. The diet includes a list of foods that need to be avoid to prevent inflammatory process.
FOODS TO AVOID/LIMITS
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PHASE 1 AND 2
Phase 1 is weeks 0-6
- Complete nutrition formula/shake should constitute 50% of total energy intake
- 5 mandatory foods
- List of allowed foods
Phase 2 is weeks 7-12
- Complete nutrition formula/shake should constitute 25% of total energy intake
- 5 mandatory foods
- Expanded list of foods
- Additional fruits and vegetables allowed for weeks 7-9 and others allowed starting week 10
PHASE 3
Maintenance
- Complete nutrition formula/shake should constitute 25% of total energy intake
- There are no mandatory foods, however, potentially harmful foods should continue to be limited or avoided
- Goal is to maintain phase 2 diet with additional foods 5 days per week
- Allowed 2 homemade “free” meals 2 days per week (some allowance for restaurant meals)
- There are few foods not allowed at all
Food groups |
Mode of introduction |
Protein |
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Dairy |
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Legumes/beans |
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Fats/oils |
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Fruits |
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Vegetables |
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Starches/grains |
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Other |
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Bibliography
- Arie Levine et al. Crohn’s Disease Exclusion Diet Plus Partial Enteral Nutrition Induces Sustained Remission in a Randomized Controlled Trial. Gastroenterology. 2019 Aug;157(2):440-450.e8. doi: 10.1053/j.gastro.2019.04.021. Epub 2019 Jun 4. PMID: 31170412 DOI: 10.1053/j.gastro.2019.04.021
- Rotem Sigall Boneh et al. Dietary Therapy With the Crohn’s Disease Exclusion Diet is a Successful Strategy for Induction of Remission in Children and Adults Failing Biological Therapy. J Crohns Colitis. 2017 Oct 1;11(10):1205-1212. doi: 10.1093/ecco-jcc/jjx071. PMID: 28525622 DOI: 10.1093/ecco-jcc/jjx071.
- Jennifer Smith, MS, RD, CSP, LD, LMT. Introduction to Crohn’s Disease Exclusion Diet. ANHI Abbot Nutrition Health Institute.
- Chun-Han Lo et al. Dietary Inflammatory Potential and Risk of Crohn’s Disease and Ulcerative Colitis. CLINICAL—ALIMENTARY TRACT| VOLUME 159, ISSUE 3, P873-883.E1, SEPTEMBER 01, 2020. Published:May 07,2020DOI:https://doi.org/10.1053/j.gastro.2020.05.011